[HTML][HTML] High‐dose intravenous immunoglobulin to treat spontaneous heparin‐induced thrombocytopenia syndrome
E Mohanty, S Nazir, JAI Sheppard, DA Forman… - Journal of Thrombosis …, 2019 - Elsevier
Essentials• Spontaneous HIT syndrome clinically/serologically resembles HIT but without
proximate heparin.• Rarely, spontaneous HIT syndrome complicates total knee arthroplasty
surgery.• Mesenteric vein thrombosis is a rare presentation of spontaneous HIT syndrome.•
IVIg rapidly corrects thrombocytopenia by inhibiting heparin‐independent platelet activation.
Summary Spontaneous heparin‐induced thrombocytopenia (HIT) syndrome is an
autoimmune HIT (aHIT) disorder characterized by thrombocytopenia, thrombosis, and HIT …
proximate heparin.• Rarely, spontaneous HIT syndrome complicates total knee arthroplasty
surgery.• Mesenteric vein thrombosis is a rare presentation of spontaneous HIT syndrome.•
IVIg rapidly corrects thrombocytopenia by inhibiting heparin‐independent platelet activation.
Summary Spontaneous heparin‐induced thrombocytopenia (HIT) syndrome is an
autoimmune HIT (aHIT) disorder characterized by thrombocytopenia, thrombosis, and HIT …
