High-density infiltration of V-domain immunoglobulin suppressor of T-cell activation up-regulated immune cells in human pancreatic cancer
X Xie, C Xuan, T Li, L Wang, L Teng, J Liu - Pancreas, 2018 - journals.lww.com
X Xie, C Xuan, T Li, L Wang, L Teng, J Liu
Pancreas, 2018•journals.lww.comObjectives V-domain immunoglobulin suppressor of T-cell activation (VISTA) is constitutively
expressed in hematopoietic lineage and is highly up-regulated in tumor infiltrated myeloid
cells and regulatory T-cells in animal models. However, its expression in human pancreatic
tumor microenvironment remains unknown. In this research, we aimed at the expression of
VISTA in human pancreatic cancer samples. Methods
expressed in hematopoietic lineage and is highly up-regulated in tumor infiltrated myeloid
cells and regulatory T-cells in animal models. However, its expression in human pancreatic
tumor microenvironment remains unknown. In this research, we aimed at the expression of
VISTA in human pancreatic cancer samples. Methods
Abstract
Objectives
V-domain immunoglobulin suppressor of T-cell activation (VISTA) is constitutively expressed in hematopoietic lineage and is highly up-regulated in tumor infiltrated myeloid cells and regulatory T-cells in animal models. However, its expression in human pancreatic tumor microenvironment remains unknown. In this research, we aimed at the expression of VISTA in human pancreatic cancer samples.
Methods
Lippincott Williams & Wilkins