Use of glycan microarrays to explore specificity of glycan-binding proteins

DF Smith, X Song, RD Cummings - Methods in enzymology, 2010 - Elsevier
Microarrays of defined glycans represent a high throughput approach to determining the
specificity of lectins, or more generally glycan-binding proteins (GBPs). The utility of a glycan
microarray is directly related to the number and variety of the glycans available on the
printed surface for interrogation by GBPs. The Consortium for Functional Glycomics (CFG),
funded by the National Institute of General Medical Sciences (NIGMS), has generated a
glycan microarray available to the public as an investigator-driven resource, where …