Long-term efficacy of BCG vaccine in American Indians and Alaska Natives: a 60-year follow-up study

NE Aronson, M Santosham, GW Comstock, RS Howard… - Jama, 2004 - jamanetwork.com
ContextThe duration of protection from tuberculosis of BCG vaccines is not known.
ObjectiveTo determine the long-term duration of protection of a BCG vaccine that was
previously found to be efficacious. DesignRetrospective record review using Indian Health
Service records, tuberculosis registries, death certificates, and supplemental interviews with
trial participants. Setting and ParticipantsFollow-up for the period 1948-1998 among
American Indians and Alaska Natives who participated in a placebo-controlled BCG vaccine …