Vezf1/DB1 is an endothelial cell-specific transcription factor that regulates expression of the endothelin-1 promoter
J Aitsebaomo, ML Kingsley-Kallesen, Y Wu… - Journal of Biological …, 2001 - ASBMB
Coordinated gene regulation within the vascular endothelium is required for normal
cardiovascular patterning during development and for vascular homeostasis during
adulthood, yet little is known about the mechanisms that regulate endothelial transcriptional
events. Vascular endothelial zinc finger 1 (Vezf1)/DB1 is a recently identified zinc finger-
containing protein that is expressed specifically within endothelial cells during development.
In this report, we demonstrate that Vezf1/DB1 is a nuclear localizing protein that potently and …
cardiovascular patterning during development and for vascular homeostasis during
adulthood, yet little is known about the mechanisms that regulate endothelial transcriptional
events. Vascular endothelial zinc finger 1 (Vezf1)/DB1 is a recently identified zinc finger-
containing protein that is expressed specifically within endothelial cells during development.
In this report, we demonstrate that Vezf1/DB1 is a nuclear localizing protein that potently and …
