[HTML][HTML] Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver
FT Yen, M Masson, N Clossais-Besnard… - Journal of biological …, 1999 - ASBMB
The lipolysis-stimulated receptor (LSR) is a lipoprotein receptor primarily expressed in the
liver and activated by free fatty acids. Antibodies inhibiting LSR functions showed that the
receptor is a heterotrimer or tetramer consisting of 68-kDa (α) and 56-kDa (β) subunits
associated through disulfide bridges. Screening of expression libraries with these antibodies
led to identification of mRNAs derived by alternate splicing from a single gene and coding
for proteins with molecular masses matching that of LSR α and β. Antibodies directed …
liver and activated by free fatty acids. Antibodies inhibiting LSR functions showed that the
receptor is a heterotrimer or tetramer consisting of 68-kDa (α) and 56-kDa (β) subunits
associated through disulfide bridges. Screening of expression libraries with these antibodies
led to identification of mRNAs derived by alternate splicing from a single gene and coding
for proteins with molecular masses matching that of LSR α and β. Antibodies directed …
