FlOure. A, Photomicrograph of patient's peripheral blood smear demonstrating large size, gray color, and hypogranular character of platelets.(Romanovsky stain; original magnification• B, Peripheral blood smear showing normal platelets. mal dominant inheritance has been suggested by one study. 6 Most patients with gray platelet syndrome have mild thrombocytopenia and some clinical features of impaired primary hemostasis, such as epistaxis and spontaneous bruisingT; however, serious hemorrhage has been an infrequent occurrence. We report an additional patient with gray platelet syndrome in whom subgaleal and intracranial hemorrhage developed, which was successfully managed with platelet infusions and the antifibrinolytic agent~-aminocaproic acid.