Congenital adrenal hyperplasia owing to 21-hydroxylase deficiency: growth, development, and therapeutic considerations
CJ Migeon, AB Wisniewski - Endocrinology and Metabolism …, 2001 - endo.theclinics.com
Congenital adrenal hyperplasia (CAH) owing to 21-hydroxylase deficiency is a disorder that
results in decreased biosynthesis of cortisol and, in some cases, aldosterone. CAH also
results in increased secretion of the anabolic steroid androstenedione and the mildly salt-
wasting steroids progesterone and 17-hydroxyprogesterone? The goal of treatment is to
replace the hormones a patient is missing and to suppress the hormones produced in
excess. Both the lack of therapy and overtreatment can result in major problems with growth …
results in decreased biosynthesis of cortisol and, in some cases, aldosterone. CAH also
results in increased secretion of the anabolic steroid androstenedione and the mildly salt-
wasting steroids progesterone and 17-hydroxyprogesterone? The goal of treatment is to
replace the hormones a patient is missing and to suppress the hormones produced in
excess. Both the lack of therapy and overtreatment can result in major problems with growth …
