In vitro model for developmental progression from vasculogenesis to angiogenesis with a murine endothelial precursor cell line, MFLM-4
AL Akeson, SK Brooks, FY Thompson… - Microvascular …, 2001 - Elsevier
In the embryo, vascular networks are developed through both vasculogenesis, the assembly
of vessels from endothelial progenitor cells or hemangioblasts, and angiogenesis, the
sprouting of vessels from preexisting capillaries. Cell culture models using endothelial cells
(EC) and various extracellular matrix components have been useful in understanding the
cellular and molecular factors involved in angiogenesis. However, there are few models of
vasculogenesis. Using a murine endothelial precursor cell line, MFLM-4, derived from e14. 5 …
of vessels from endothelial progenitor cells or hemangioblasts, and angiogenesis, the
sprouting of vessels from preexisting capillaries. Cell culture models using endothelial cells
(EC) and various extracellular matrix components have been useful in understanding the
cellular and molecular factors involved in angiogenesis. However, there are few models of
vasculogenesis. Using a murine endothelial precursor cell line, MFLM-4, derived from e14. 5 …
