[HTML][HTML] Interaction of β2-glycoprotein I with members of the low density lipoprotein receptor family
MTT Pennings, M Van Lummel, R Derksen… - Journal of thrombosis …, 2006 - Elsevier
The antiphospholipid syndrome (APS) is a non-inflammatory autoimmune disease
characterized by arterial and/or venous thrombosis and/or pregnancy morbidity in the
presence of autoantibodies that recognize beta2-glycoprotein I (β 2 GPI) bound to
phospholipids. We have previously demonstrated that dimerization of β 2 GPI by
autoantibodies induces platelet activation, involving the platelet receptor apolipoprotein E
receptor 2'(apoER2′) a receptor belonging to the low-density lipoprotein receptor (LDL-R) …
characterized by arterial and/or venous thrombosis and/or pregnancy morbidity in the
presence of autoantibodies that recognize beta2-glycoprotein I (β 2 GPI) bound to
phospholipids. We have previously demonstrated that dimerization of β 2 GPI by
autoantibodies induces platelet activation, involving the platelet receptor apolipoprotein E
receptor 2'(apoER2′) a receptor belonging to the low-density lipoprotein receptor (LDL-R) …
