[HTML][HTML] Characterization of dual leucine zipper-bearing kinase, a mixed lineage kinase present in synaptic terminals whose phosphorylation state is regulated by …
M Mata, SE Merritt, G Fan, GG Yu… - Journal of Biological …, 1996 - ASBMB
The biochemistry and regulation of dual leucine zipper bearing kinase (DLK), a member of
the mixed lineage kinase or MLK subfamily of protein kinases, was examined in the nervous
system. DLK transcript expression in the nervous system was predominantly neuronal. DLK
protein was present in synaptic terminals where it was associated with both plasma
membrane and cytosol fractions. Within these two fractions, DLK had differing
characteristics. Cytosolic DLK existed in both a phosphorylated and dephosphorylated state; …
the mixed lineage kinase or MLK subfamily of protein kinases, was examined in the nervous
system. DLK transcript expression in the nervous system was predominantly neuronal. DLK
protein was present in synaptic terminals where it was associated with both plasma
membrane and cytosol fractions. Within these two fractions, DLK had differing
characteristics. Cytosolic DLK existed in both a phosphorylated and dephosphorylated state; …
